Research & Clinical Trials

This is a tool to identify specific Alzheimer’s clinical trials. Just click on the start button and enter the information as prompted. You will be provided with a list of the trials within your geographic area.

Are you a caregiver for a person with dementia who is receiving home care?

If you are a caregiver living approximately 2 or more hours away from your care recipient, you may be eligible to participate in a new research study evaluating the administration of a non-drug intervention designed to help long-distance caregivers of persons with dementia.

You may be eligible to participate if you:

• Are a caregiver age 21 or older
• Are living about 2 hours or more away from your care recipient
• Have a care recipient with dementia AND who is receiving home care

If eligible, you will receive:

• Individualized support from dementia experts, delivered remotely via the use of a tablet.
• Tailored dementia education and resources
• A new tablet for the study, which is yours to keep

To learn more, contact the Project Director, Evan Chunga, at Richard.Chunga001@umb.edu or contact the Principal Investigator, Dr. Verena Cimarolli at vcimarolli@leadingage.org or 202-508-9411.
Exp. 7/31/23

Neurostimulation for Cognitive Enhancement in Alzheimer’s Disease (NICE-AD)

The prevalence of Alzheimer's Disease (AD) is rising, but existing medications provide only modest control of cognitive decline and associated symptoms, and novel therapies are urgently needed. This randomized sham-controlled trial will determine if an innovative low-risk remotely-supervised transcranial Direct Current Stimulation (tDCS) applied over the area of the dorsolateral prefrontal cortex for 30 minutes at the intensity of 2 mA five times per week for 6 months at home can improve cognitive performance and symptoms and modulate neuroimaging markers of neuroplasticity in 100 patients with mild to moderate AD. If effective, this novel intervention can substantially enhance AD symptom management at home, improve quality of life of AD patients and their families, and reduce burden associated with this debilitating illness. For more information, contact NICEAD@einsteinmed.eduor (718) 430-3978.

STRUMM (Supportive Technology Resources through Usability & Machine-learning Methods) Project

The goal is to provide support for memory or cognitive challenges encountered with everyday activities. If you or your loved one is living with traumatic brain injury (TBI), stroke-related cognitive impairment (SCI), or mild cognitive impairment (MCI), then you or your loved one may be eligible to take part in this research study. Participants of this study will be asked to take part in a 2–3 hour interview that will ask questions such as what types of challenges aging adults living with TBI, SCI, or MCI encounter in everyday and community activities (including social activities) and the features and components of the software support system that could be potentially beneficial.

This interview will be conducted virtually via Zoom but can be done in-person, if necessary, at our offices at the Center on Aging and Behavioral Research at Weill Cornell Medicine.  Participants will receive financial compensation for their time and effort.

For more information, please contact us at:  (646) 962-7141 or AgingBehavioralRsrch@med.cornell.edu.

Dementia Caregiving Study at Weill Cornell Medicine

Researchers at Weill Cornell Medicine are conducting a research study examining well-being and resource use in dementia caregivers. The aim of this study is to identify and examine the needs of caregivers, and to identify the types of resources and support services that would be most beneficial to promote psychological well-being. We are contacting you because you were identified as primary caregiver for a loved one living with dementia.

To be eligible to participate, individuals must be a primary caregiver for a loved one with dementia living in the community and be 18-89 years of age. If you are eligible and agree to participate, you will be asked to complete an online survey lasting 20-30 minutes. Then, you will be given the option to participate in a follow-up phone interview with a member of our research staff. This interview will take approximately 45-60 minutes and can be completed in-person, via telephone, or Zoom videoconferencing. You will be asked to answer some questions about your demographic characteristics, care responsibilities, challenges experienced, and ways you have coped with those challenges. Then, you’ll be asked to answer some questions about your use of community resources, barriers to accessing and using resources, and suggestions for resources that you would be interested in using in the future based on your own personal needs.

You will receive a stipend of $20 for your completed study visit. For those who choose to participate in the open-ended interview, you will be compensated with another $40. This will be paid to you in the form of a ClinCard.  ClinCard can be used as a credit or debit card and funds will be available to you within 5 business days after you complete your study visit.

Your participation in this study is voluntary. You can decide not to participate at any time. If you are interested in participating or you would like more information about the study, please contact the study’s project manager, Megan McCarthy at mem4017@med.cornell.edu or 917-740-5075. You can also contact the study’s Principal Investigator, Dr. Francesca Falzarano, at fbf4001@med.cornell.edu or 646-481-2858.

Virtual Handfeeding Training for Care Partners

Participate in a clinical study investigating the effects of virtual handfeeding coaching and feedback on care partner use of strategy with a person with dementia.

Who can participate?
Adults/care partners who care for a person with dementia who is age 65 or older, and have access and knowledge of using Zoom.

What will you do?
Participate in 2-4 virtual training sessions per week of approximately 30 minutes. Approximate commitment time of 4-6 weeks.

Where and when?
In your home virtually and scheduled during your availability. Must reside in New York State.

Contact: Kelly Trejos Ibata, Speech-Language Pathologist Doctoral Student kelly.trejos-ibata@rm.edu

View Flyer

NIH-Funded Project Seeks Advisory Committee Members

Researchers are seeking long-distance caregivers and home care aides to help guide a new study.

The LeadingAge LTSS Center @UMass Boston is seeking two long-distance caregivers and two home care aides to join an advisory committee for a new research project.

The research project, funded by the National Institutes of Health, aims to develop an intervention that can address the specific needs of long-distance caregivers who experience caregiving burden. The intervention will be developed with the help of a caregiving expert advisory committee.

The project’s advisory committee already includes one researcher with expertise in the field of family caregiving and one leader of a caregiver support organization.

Advisory committee members will be asked to attend four meetings over a five-month period, beginning Spring 2022. Each advisory committee meeting will be held on Zoom at a date and time convenient for all members. Members of the advisory committee will receive a small stipend for each meeting.

If you know of a long-distance caregiver or home care aide who fits the study requirements and is willing to serve, please contact Project Director Richard Evan Chunga (Richard.chunga001@umb.edu or 718-551-4476). You may also reach out to Dr. Verena Cimarolli, the study’s principal investigator (vcimarolli@leadingage.org or 202-508-9411).

Dementia Caregiver Research Study

Do you have a family member with dementia?
To participate, please contact Alison Zeng
(senior at Dartmouth College) at Alison.Zeng.22@dartmouth.edu

Chinese Flyer (PDF)

*Affiliated with Dartmouth College, Hanover NH
We are studying Chinese American and non-Chinese American individuals who care for a family member with dementia. Share your experiences in our brief survey!

Criteria for participation:

• Must be a primary caregiver for a family member with dementia
• Family caregivers of people living in care facilities are eligible!
• Both Chinese American and non-Chinese American caregivers needed

As a token of appreciation, participants will be financially compensated for their time

Seeking caregivers for participation in survey regarding financial exploitation

Are you a caregiver to a patient with a neurodegenerative condition? You are invited to participate in a survey examining the prevalence of financial exploitation and scams in those with neurodegenerative conditions such as dementia. This is a survey study

• Survey can be completed online or via telephone
• Estimated completion time = ~20 minutes
• All analysis will be conducted at the group level

If interested, please contact: Preeti Sunderaraman, PhD at ps2548@cumc.columbia.edu

IRB-AAAT1976 (Y01M00) IRB Exemption Date: 09/03/2020

Take part in our clinical study

The LUCIDITY study is sponsored by TauRx Therapeutics Ltd., a leader in neurodegenerative disease research. As you may be aware, there is an urgent need for better treatments for Alzheimer’s disease (AD) as current therapies help with the symptoms of AD but do not stop the disease from progressing.

If you or a loved one are experiencing memory loss, or have been diagnosed with Mild Cognitive Impairment (MCI or MCI-AD), Probable/Early Alzheimer’s disease, or Mild-Moderate Alzheimer's disease, you or a loved one may be eligible to participate in our clinical research study.

Learn more  Pre-Qualify

Clinical Trial Sites in New York City

These Alzheimer’s clinical trial sites in New York City welcome individuals with memory issues to make an appointment for evaluation. After screening and initial testing, for qualifying candidates the site will suggest appropriate trials for consideration.

Biovie Trials

BioVie is currently conducting a late-stage clinical trial whereby the first fully qualifying 320 patients with mild to moderate Alzheimer’s Disease may participate. Study participants will receive extensive medical testing and
treatments. Participants will have about a 50% (1 in 2) chance of receiving NE-3107 and about a 50% (1 in 2) chance of receiving placebo (an inactive capsule that looks like the NE-3107). The study is double-blind meaning that neither you nor the Study Doctor will know who is receiving NE-3107 or placebo. Study participants may be among the first people to have the chance to receive NE-3107, with its unique dual mechanism of action, while contributing to the advancement of medical understanding in treating Alzheimer’s.

Who is eligible to participate?

• People who are from 60 to 85 years of age at the beginning of their study participation
• Show medical evidence of mild to moderate Alzheimer's Disease, for instance:
• May be getting lost in familiar places
• May become confused while preforming previously routine tasks
• New or worsening challenges with language, writing, math, or drawing
• Decision making may be difficult, or errors in decision making are new
• Other may notice words, phrases, or questions are repeated
• Generally healthy enough to participate in all study activities and travel
• Have shown an important decline in memory and daily functions from a previous higher level of ability
• Cause of Memory loss is not due to stroke, cardiovascular, or other non-Alzheimer's causes
• No episodes of violence or aggression
• Not taking insulin
• Has never been diagnosed with breast cancer

To Get Involved today, email: bioviepharma.com

Other Research Trials in New York City

NYU Langone Health

The NYU Langone Vaccine Center is seeking healthy adult volunteers who are interested in participating in clinical research for a COVID-19 vaccine study.

LEAF: Life Enhancing Activities for Family Caregivers

Do you care for someone with Alzheimer's Disease?
Many family caregivers of people with Alzheimer's Disease experience physical and emotional changes as a result of their caregiving.  Research shows that increasing one’s levels of positive emotion can lower stress and increase the ability to cope with existing stress. We are interested in the effects of applying these techniques with Alzheimer's family caregivers.

Who is eligible to participate?
If you are the primary caregiver of a person diagnosed with Alzheimer's Disease
and have access to a reliable Wi-Fi internet connection, you may be eligible!

Participating in the LEAF study involves:
Taking part in a positive emotions building study program via:

• Six (6) weekly hour-long video sessions with a facilitator OR a
  6-week self-guided online program (you would be randomly chosen for video sessions or the online program)
• Nightly home practice to reinforce the skills
• Online surveys

Visit us at: http://leafstudy.ucsf.edu and fill out our eligibility survey
Email us at: LEAFstudy@northwestern.edu
Call us at: 312-503-5247 (Central time)

New Clinical Study Currently Enrolling People with Memory Loss and Elevated Blood Sugar

The Elevage study (NCT03980730) is being conducted to evaluate the efficacy and safety of azeliragon in patients who are experiencing memory loss and have elevated blood sugar or Type 2 Diabetes.

To qualify for participation in the study you must:

• Be 50-85 years of age (inclusive)
• Currently be taking medication for memory loss (including Aricept (donepezil), Exelon (rivastigmine), Razadyne or Reminyl (galantamine) and/or Namenda or Ebixa (memantine), etc.)
• Have elevated blood sugar (A1c 6.5% to 9.5%)
• Have a reliable caregiver/study partner

To learn more, click here.

Join a Research Study: Neurodegeneration-Associated Psychiatric Syndromes

Principal Investigator: Edward Huey, M.D.
Seeking participants for an observational research study looking at how dementias (like Alzheimer’s disease) can affect mood and behavior.

• Participation involves coming in with a study partner (someone who knows you well) for one voluntary, 4-5 hour visit to answer questions about recent mood and emotions and complete an MRI scan
• Participants will be compensated $50-$100

This study is recruiting participants with dementia, including:

• People who have been diagnosed with Alzheimer’s disease
• Who are between 40-90 years old,
• And who speak English or Spanish.

How do I participate?
If you are interested in becoming involved in this study or learning more, please contact the research team at (212) 305-3187 or HueyResearchTeam@cumc.columbia.edu

Weill Cornell Medicine - Family Caregiver Research Study

Do you care for someone with dementia and pain? Are you a family member or unpaid caregiver?

If so, we want to learn from you! You are invited to participate in a one-time, 20-30 minute in person or phone interview. To thank you for your time, you will be provided with a $15 gift card after completing the interview.

For more information or to participate, please contact Dr. Riffin: 212-746-7317 or acr2213@med.cornell.edu

Care Partners Program

If you are caring for a loved one with Alzheimer’s or other dementias, you might be eligible to take part in a research study that Weill Cornell Medicine is conducting. You will learn strategies to reduce stress, enhance caregiving skills, and improve overall well-being. Your loved one will receive cognitive training or mental stimulating exercises.

The study has a duration of 12 months. You and your loved one can participate from the comfort of your home at no cost. You will receive a laptop with Wi-fi capability during study participation to access study-related material and content. You will also receive financial compensation for your time and effort.

For more information, please contact us at:
(646) 962-7141 or AgingBehavioralRsrch@med.cornell.edu

Seeking individuals with Alzheimer’s disease who experience agitation

The Escitalopram for Agitation in Alzheimer’s Disease (S-CitAD) study is a 12-week trial of escitalopram taking place at Memory Disorders Clinic at New York State Psychiatric Institute.

The S-CitAD Research Study is looking for volunteers who:

• Have been diagnosed with Alzheimer’s disease
• Experience feelings of irritability, restlessness, frustration, or anger
• Have a study partner who can participate in the study

All participants receive: Free parking at each visit, Psychosocial counseling provided to all eligible participants, All visit procedures administered at no cost.

Call 646-774-8671 for more information.

Survey for Caregivers

Are you currently providing care to someone with dementia? Are you employed or were you employed at any point while caring for your friend, family member, or neighbor with Alzheimer’s disease or Dementia? If you answered ‘yes’, then we would love to hear from you!

Researchers at the University at Albany School of Public Health are looking for interested individuals to participate in a study that seeks to understand the experiences of working caregivers. This anonymous survey should take about 10-15 minutes of your time, and can be accessed at the following link:

https://www.surveymonkey.com/r/WorkandCaregiving

Participate in a research project on Alzheimer's and Caregiving

The purpose of this project is to identity the types of decisions that caregivers face as their family member or friend progresses through the stages of Alzheimer's.

Learn more

Cognite Early Stage Alzheimer's Clinical Trial

Imagine making an impact

Consider taking part in a clinical trial that is currently enrolling to treat for early stage Alzheimer’s disease

What is the Cognite Trial?

The Cognite Alzheimer’s Clinical Trial is enrolling men and women who have signs of early stage Alzheimer’s disease. The clinical trial is evaluating whether an investigational combined treatment slows down, arrests, or reverses early stage Alzheimer’s disease.

To qualify, participants must:

• Be between 55 and 79 years old
• Have at least 8 years of education
• Have noticed, or have had a loved one notice, changes in your memory
• Have noticed changes in their normal, everyday behavior
• Attend all study visits with a study partner with whom the
  participant has frequent contact
• Be in good general health

Are you or someone you know experiencing memory loss? Are you or someone you know having trouble retaining information? This may be an indication of early stage Alzheimer’s disease, which is a type of dementia that causes problems with an individual’s memory, thinking, and behavior.

For more information:

646-678-4196 | cognitetrial.com

Learn more (PDF)

Treatment of Psychosis and Agitation in Alzheimer’s Disease

This research study, funded by the NIH, involves a 12-week double-blind treatment trial in which outpatients with Alzheimer’s disease (age 55-95 years) who have agitation/aggression with or without psychosis (hallucinations or delusions) will receive either low-dose lithium or placebo. Patients are allowed to receive other specific psychiatric medications if needed during the study, and will be closely monitored by physicians who specialize in memory disorders. Patients will receive open treatment with lithium, if clinically indicated, after completing the 12-week double blind trial.
For more information, please contact Jesse Strickler at (646) 774-8668 or strickl@nyspi.columbia.edu.
ClinicalTrials.gov Identifier: NCT02129348